Molecular characterization of human adenomyosis
نویسندگان
چکیده
منابع مشابه
Molecular characterization of human adenomyosis.
Adenomyosis is a common gynaecological disorder characterized by the abnormal growth of endometrium into the myometrium and myometrial hypertrophy/hyperplasia. Uterine fibroids are benign neoplasms of the myometrium, and they represent a diagnostic pitfall for adenomyosis. In this study, we have used the genome-wide Affymetrix U133 Plus 2.0 microarray platform to compare the gene expression pat...
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Adenomyosis, an estrogen-dependent inflammatory disease, is defined as the presence of endometrial glands and stroma deep within the myometrium [1]. The main clinical features of adenomyosis are dysmenorrhea and menorrhagia, which are significantly associated with peritoneal endometriosis in infertile patients at reproductive age [2,3]. The only difference between adenomyosis and endometriosis ...
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Tensin is a focal-adhesion molecule that binds to actin filaments and interacts with phosphotyrosine-containing proteins. To analyse tensin's function in mammals, we have cloned tensin cDNAs from human and cow. The isolated approx. 7.7-kb human cDNA contains an open reading frame encoding 1735 amino acid residues. The amino acid sequence of human tensin shares 60% identity with chicken tensin, ...
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ژورنال
عنوان ژورنال: Molecular Human Reproduction
سال: 2006
ISSN: 1360-9947,1460-2407
DOI: 10.1093/molehr/gal076